DEVELOPMENT OF DROPLET DIGITAL PCR-BASED ASSAYS TO QUANTIFY HIV PROVIRAL AND INTEGRATED DNA IN BRAIN TISSUES FROM VIREMIC INDIVIDUALS WITH ENCEPHALITIS AND VIRALLY SUPPRESSED AVIREMIC INDIVIDUALS

ABSTRACT Although combination antiretroviral therapy (cART) can suppress the replication of HIV, the virus persists and rebounds when treatment is stopped.To find a cure that can eradicate latent reservoir, a method should be able to quantify the lingering HIV.Unlike other digital PCR technologies, droplet digital PCR (ddPCR), provides absolute qua

Special vehicles named flat transporters are used to deliver heavy ship assembly blocks in shipyards.Because each movement of assembly blocks among workshops needs transporters and the transportations are time-consuming, the scheduling of transporters is important for maintaining the overall production schedule of assembly blocks.This paper conside

The fluid film lubrication problem is usually solved using classical Reynolds equation-based modeling to predict fluid film behavior such as pressure distribution and oil film thickness, which requires pressure boundary conditions at the locations of film formation and separation.When applying the classical approach to practical applications like r

Abstract Background MicroRNAs (miRNAs) are endogenous small non-coding RNAs that play important roles in the regulation of diverse biological processes in eukaryotes.Chinese perch (Siniperca chuatsi) is one of the most economically important fish species Audio Turntable Stylus widely cultured in China.Growth is an extremely important characteristic